Biotics Research St. John's Forte - 60 Capsules
St. John’s Wort (Hypericum perforatum L.). In the Chinese tradition, St. John’s Wort is classified as a cooling herb, utilized primarily as a detoxifier. Its conventional use, however, is for symptoms associated with unwanted mood patterns. The biologically active components include hyperforin, hypericin, flavonoids, xanthones, procyanidines, and amino acids. As opposed to one specific compound, the total herbal extract is considered to be the active substance, with a number of active compounds speculated to contribute to the mood enhancing efficacy.
Daminana (Turnera diffusa). Damiana is traditionally used as a general tonic for the nervous, endocrine, and reproductive systems. It is also noted for its benefits in anxiety and nervousness and for boosting and maintaining both mental and physical capacity. Siberian Ginseng (Eleutherococcus senticosus). The traditional use of Siberian Ginseng is as an adaptogen for increasing endurance and improving memory, and to enhance overall well-being.11 It is considered an invigorating tonic.
B vitamins as positive mood enforcements Thiamin is a required component in carbohydrate metabolism. Riboflavin functions as an important molecule in intermediary metabolism. Folate levels that are low prevail in melancholic depression, and an elevated score on a depressive symptom questionnaire (PHQ score of ≥10) has been inversely associated with folate status.
Niacin’s primary function in the body is as a precursor to the coenzymes NAD+ and NADP+; however it also aids in proper functioning of the nervous system. Shortfalls have been associated with mental modifications, which may include depression, irritability, delirium and emotional instability. Pyridoxal 5-phosphate (P5P), the active form of vitamin B6, functions as an important component in the synthesis of neurotransmitters, including γ-aminobutyric acid (GABA), serotonin, dopamine, norepinephrine and epinephrine.
Vitamin B12 is involved in numerous enzymes that require it as a coenzyme, including its essentiality for the transformation of neurotransmitters, and the methylation of compounds in the brain via its involvement in the metabolism of S-adenosyl methionine and methionine. A deficiency in vitamin B12 can contribute to feelings of anxiety and stress, as irritability, and mental confusion. Biotin participates as an essential coenzyme for five carboxylases.
Additional nutritional components as adjuncts to mood support Inositol, an essential component of every cell, functions as a key ingredient for the membrane lipid phosphatidylinositol. In certain circumstances, in vivo synthesis may be inadequate to meet daily needs. Choline serves as a precursor for the synthesis of both the neurotransmitter acetylcholine, and the membrane phospholipid phosphatidylcholine. It serves to support with cognitive function.
Chromium is well known for its potentiating action on peripheral insulin.
Magnesium is well recognized as a relaxant mineral. In one study the authors postulate that “serum Mg level...may be involved in the mechanism for the progression of depressive mood or stress perception in relatively healthy, adult women.”
The synergistic association of the St. John’s Forte™ components support normal mood, while also having a beneficial effect on anxiety and nervousness.
Cautions: St. Johns’s Forte™ is not recommended for pregnant or lactating women, those taking protease inhibitors or nonnucleoside reverse transcriptase inhibitors, those taking immunosuppresive drugs such as cyclosporine, those taking warfarin or dioxine, those taking drugs for treating diabetes, those with a history of breast cancer, or those having Alzheimer’s or Parkinson’s disease